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Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration ; 23(Supplement 1):36-37, 2022.
Article in English | EMBASE | ID: covidwho-2160819

ABSTRACT

Introduction: Poliomyelitis is an inflammatory viral disease that causes destruction of motoneurons. Despite being eradicated in Brazil, it left sequelae on survivors, making them need continuous treatments. Considering the sequelae and new symptoms related to Post-Polyomyelitis Syndrome (PPS), these patients may be vulnerable in the Covid-19 Pandemic. Objective(s): To characterize and analyze the prevalence of risk factors for contracting COVID-19 as well as developing its severe form in patients with Sequelae of Poliomyelitis and Post-polio Syndrome. Method(s): An epidemiological study was carried out through an online questionnaire, where epidemiological, physical and psycho-emotional health issues were addressed in the pandemic. Approved by CEP UNIFESP under Ndegree4,087,073. Result(s): 383 responses were obtained in the following groups: Sequelae of Poliomyelitis (GP-49%;n=190) and PPS (GPPS-50.4%;n=193). Female and age 50-59 years were more prevalent. The most common disorders were monoparesis (38.9% GP;21.7% GSPP), followed by paraparesis in GP (18.9%) and tetraparesis in GSPP (16.6%). As for comorbidities, 37.4% of the GP and 37.3% of the GSPP reported Hypercholesterolemia;42.6% (GP) and 47.1% (GSPP) Hypertension and 19.5% (GP) and 14.5% (GSPP) Diabetes. About 29% of the GP were obese against 35.2% (GSPP). In the physical aspects, 57.9% (GP) and 65.8% (GSPP) reported worsening in the quarantine and 19.7% (GSPP). Discussion(s): Patients affected with Poliomyelitis had a proportion of Hypercholesterolemia, Hypertension and Diabetes about twice that of the Brazilian population over 18 years (14.6%;23.9 and 7.7%, respectively) (1). In this sense, research shows an increased risk for severity and death from COVID- 19 in patients with Hypertension (2,3), Diabetes (2,3) and Hypercholesterolemia (2). People with disabilities can be disproportionately impacted by emergencies and the disruption of services can be a contributing factor (4). This impact could be perceived by the reports of worsening in the physical aspect during the quarantine, especially in GPPS who have a higher frequency of tetraparesis, which can difficult to carry out the necessary hygiene measures. Conclusion(s): Poliomyelitis survivors have comorbidities, in addition to limitations and dependence in their activities of daily living that can make them more vulnerable to contagion by COVID-19 as well as making them more susceptible to the severe form of the disease.

2.
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Multiple Sclerosis Journal ; 28(2):NP24-NP25, 2022.
Article in English | EMBASE | ID: covidwho-1724267

ABSTRACT

Introduction: Multiple Sclerosis is a chronic autoimmune disease that affects the Central Nervous System, causing destruction of myelin, and it is believed to be caused by a combination of environmental and genetic factors. Objectives: To analyze the effect of telerehabilitation in fatigue on Multiple Sclerosis patients during the isolation period of the pandemic of COVID-19. Methods: This is a retrospective study through the analysis of medical records, with adult individuals affected by Multiple Sclerosis, through the scores of some scales. They are EDSS (Expanded Disability Status Scale) and MFIS (Modified fatigue impact scale). Results: The Wilcoxon Signed Test Station was applied to verify the differences between the moments of pre and post-intervention. In general, the MFIS scores at the time of pre-intervention are higher than the post-intervention. Spearman's correlation analysis was applied, verifying the degree of relationship between the variables of the scale results and age, sex and EDSS. The EDSS demonstrated a good relationship with the MFIS. Conclusions: We show that telerehabilitation performed during the pandemic period has a positive effect on fatigue of patients with Multiple Sclerosis.

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